Offering 2 indoor swimming pools, the 5-star Regina Isabella-Resort Spa Restaurant Lacco Ameno is nestled in Lacco Ameno, which extends on the first slopes of Mount Epomeo, 25 minutes' walk from the low-key sand Chiaia Beach. Featuring 105 rooms with views of the garden, the hotel is 3.5 km from the Italian Giardini Ravino Botanical Garden.

This deluxe hotel boasts prime location just near the Church of Santa Restituta. The Regina Isabella-Resort Spa Restaurant offers access to Port of Casamicciola Terme, located 30 minutes' walk away. The own beach is 50 metres away. The nearby cultural experience includes the Archaeological Museum of Pithecusae, which is 0.9 km away. The nearest bus stop is Parco Negombo, about 5 minutes away by car.

Along with free Wi-Fi and a flat-screen TV with satellite channels, the soundproofed rooms offer a minibar fridge, and separate bathrooms with a bidet, a separate toilet, and a shower. The en suite bathrooms come with a bidet and a separate toilet.

A free breakfast is served in Regina Isabella-Resort Spa Restaurant daily. The à la carte Sporting restaurant welcomes guests with seafood dishes. This accommodation has the cocktail bar with live music and a TV. It also serves evening cocktails. There is a seafood restaurant serving Italian food about 200 metres away.